I think so when I look at this headset. But I don't see much sense in it, because the Astro A50 (2019 version) already comes with a base station on which you can place the headset. This base station serves as a radio receiver and charging station. If it's an older A50, then the Corsair ST100 can make perfect sense. It has two USB ports to which you can connect the radio receiver and a USB cable to charge the headset.