Depending on the thickness and firmness of the fibrin coatings, microbial colonization, wound edge maceration, or irritation, the moist phase should be appropriately adjusted. For example, in wounds that are covered with fibrin, have a foul odor, and are heavily colonized by germs, the application time is 15-20 minutes. In a stable wound environment with a clean wound bed and no microbial abnormalities, the application time is 5-10 minutes. Now apply ActiMaris wound gel and cover it with a sterile gauze. It can be repeated multiple times a day and over an extended period.