This 32GB RAM is 100% compatible with the Acer Altos R320 F2. Information regarding memory configuration: The following technical specifications should be considered in advance: RDIMM (Registered DIMM) or LRDIMM (Load Reduced DIMM) RAM can be installed in the device. LRDIMM memory is recommended when large memory capacities are required. RDIMM memory modules cannot be mixed with LRDIMM memory. If a memory upgrade is to be performed with the existing RAM, it must be checked which memory technology (RDIMM / LRDIMM) is currently in use. Memory slots without a processor present must not be populated. A higher memory clock speed of the memory module automatically adjusts to the clock speed set by the system. This can especially be the case with larger capacities. When using 4Rank (4Rx..) RDIMM memory, only 2 out of 3 memory slots per memory channel can be occupied.