The book "Bioengineering and Cancer Stem Cell Concept" offers a comprehensive examination of the role of cancer stem cells in the diagnosis, treatment, and cure of cancer. It discusses innovative methods for identifying markers for cancer stem cells as well as their respiration and metabolism. Additionally, genetic and epigenetic mechanisms, including DNA methylation and mi-RNA assembly, are analyzed in depth. Another focus is on bioinformatics techniques that provide new approaches to modeling cancer progression. The authors illuminate the differences between cancer stem cells and normal stem cells and discuss the concept of targeted therapy for cancer stem cells. Despite the controversies surrounding the theoretical explanations of the role of cancer stem cells in leukemia and solid tumors, the existence of cancer stem cells within heterogeneous cancer cell populations is increasingly recognized. The book provides valuable insights into the leading theories, including the hierarchical and stochastic models.