The book "Biomarker Discovery in the Developing World: Dissecting the Pipeline for Meeting the Challenges" is aimed at postgraduates and researchers interested in proteomics and its applications in the field of clinical biomarker development. Biomarker discovery is a central research topic for many life scientists worldwide. However, the process from discovery to validation and regulation as a diagnostic or therapeutic molecule is complex. This book provides a comprehensive overview of the various development phases of the biomarker lifecycle, with particular attention given to the emerging role of proteomics. It begins with the significance of biorepositories and biobanking practices in developing countries and subsequently addresses disease heterogeneity as well as the role of multi-omics techniques in developing innovative approaches to biomarker discovery. Further chapters focus on current omics-based platforms and mass spectrometry as a powerful technology for discovery studies and targeted validations.