The book "Chemical Permeation Enhancers in Transdermal Drug Delivery System" offers a comprehensive analysis of the technologies aimed at improving skin permeation, which are becoming increasingly important in modern drug delivery. In recent years, the field of transdermal drug delivery has rapidly evolved, leading to a variety of new approaches that increase the number of medications that can be administered through the skin. The author, Dhirendra C. Patel, explores the role of chemical and physical penetration enhancers and their impact on drug permeation through the skin. A central theme of the book is the balance between the effectiveness of these enhancers and the minimization of skin irritation, which is crucial for the future development of safe and effective transdermal systems.