The book "Computational Systems Biology" provides a comprehensive introduction to computational methods for identifying, modeling, and storing relationships between molecules, signaling pathways, and cells in living organisms. It highlights the development of the field, which has been reshaped by advances in high-throughput methodologies, genome-wide sequencing, and computational power. The authors discuss the modeling of both small metabolic and signaling pathways as well as the complex relationships in large biological systems, including entire cells and organisms. These models allow for the recognition of patterns and relationships that are not obvious when considering individual components. The book is aimed at researchers and students who wish to develop a deeper understanding of the dynamic interactions in biological systems.