The authors of this anthology address the prerequisites and possibilities of efficient communication, particularly in the area of cross-media mediation. In addition to fundamental conditions for shaping verbal, non-verbal, oral, and written communication, the contributors analyze specific cases of interaction with various target groups. The articles from different countries cover the fields of internal and external organizational communication. Cultural action conditions are explored in both the corporate and national cultural contexts. The contributions illustrate the cultural and media-specific peculiarities that communication management must take into account. Case studies provide concrete action guidelines and illustrate research findings using examples from both profit and non-profit organizations.