The book "Development of Isoniazid Loaded Silk Fibroin Microsphere" offers a comprehensive investigation into the production of microspheres using isoniazid as a model drug. The authors, Narinder Singh, Rajinderpal Kaur, and Surya Prakash Gautam, present an innovative method for creating microspheres through phase separation, characterized by their small size and good sphericity. Silk fibroin, known for its biocompatibility and biodegradability, is used as a carrier substance to optimize drug release. The study highlights the interactions between the charge and hydrophobicity of the drug molecules and their impact on the release behavior. Various analytical techniques, such as UV-Vis spectroscopy and scanning electron microscopy, are employed to assess the quality and efficiency of the microspheres. This research could represent significant advancements in the development of nanoformulations for targeted drug delivery.