The book "GAPDH: Biological Properties and Diversity" offers a comprehensive analysis and synthesis of the biomedical literature on the protein glyceraldehyde-3-phosphate dehydrogenase (GAPDH), which has been studied over a period of more than fifty years. Due to its involvement in a variety of cellular activities, GAPDH is of great interest to professionals from various fields such as cell biology, immunology, virology, and biochemistry. The book highlights the significant role of GAPDH in fertility, cancer research, and neurodegeneration, making it a valuable resource for drug development. Additionally, the function of GAPDH in relation to anesthesia is discussed. The high conservation of the protein, which is found in microorganisms such as pathogens, is also addressed, presenting challenges in the development of antimicrobial agents. For evolutionary biologists, the book provides a platform for an informed discussion about the origins of life.