"Herbal Medicine in Depression" is a comprehensive textbook that explores the role of herbal medicine in the treatment of depression. It is aimed at a wide audience, including researchers, students, and practitioners of traditional medicine. The book provides a detailed analysis of the biochemical causes of depression and examines the mechanisms of action of antidepressants. It also presents common animal and cell models used in research on this condition. Another focus is on discussing medicinal plants and bioactive compounds that are used in traditional medicine for treating depression. Additionally, advancements in nanotechnology for targeted drug delivery to the brain and future challenges for research in this area are addressed. The combination of theoretical knowledge and practical applications makes this book a valuable resource for anyone engaged with the topic.