The book "Homology Modeling: Methods and Protocols" offers a comprehensive introduction to the techniques of homology modeling, an important method for predicting the three-dimensional structure of proteins. It is aimed at scientists who wish to develop a deeper understanding of the relationship between the structure and function of proteins. The authors, Andrew J. W. Orry and Ruben Abagyan, explain the individual steps of homology modeling and provide practical case studies that address challenging modeling objectives. The detailed descriptions and implementation guidelines are designed to achieve optimal results in the laboratory. The book is part of the renowned series "Methods in Molecular Biology(TM)" and serves as a valuable resource for researchers engaged in biomedical research and looking to develop new therapeutic approaches.