The book "Immunoprotection of mice immunised with Recombinant Oligopeptidase B" offers a comprehensive investigation into the development of a vaccine against trypanosomiasis, a disease complicated by the antigenic variation of trypanosomes. The authors, Nanyiti Sarah, Alain Boulange, and George William Lubega, present innovative approaches to circumvent this challenge by utilizing conserved vaccine targets. The focus is on the serine oligopeptidase protein of trypanosomes, which has been identified as a potential candidate for vaccine development. The study's results suggest that oligopeptidase B has promising protective potential; however, further confirmations in combination with other vaccine targets are necessary. This specialized book is aimed at scientists and professionals engaged in immunology and vaccine research.