The book "Intracranial Pressure and Brain Monitoring XV" offers a comprehensive collection of research papers presented at the 15th International Symposium on Intracranial Pressure Measurement and Brain Monitoring (ICP). This publication brings together the latest insights and developments in the pathophysiology, biophysics, monitoring, and treatment of traumatic brain injuries and hydrocephalus. The contributions come from leading experts in neurocritical care, physiology, physics, engineering, and neurosurgery who have made significant advancements in this translational research field. All articles have been selected through a rigorous peer-review process and cover a wide range of topics, from current research findings to clinical studies and experimental investigations. This collection continues the tradition of publishing important works from the ICP symposia and is aimed at professionals who wish to stay informed about the latest developments in this field.