The book "Maroteaux Lamy syndrome and Hurler-Scheie syndrome" by Aamir Al Mosawi provides a comprehensive analysis of the clinical diagnostics of rare genetic metabolic disorders, particularly mucopolysaccharidoses. In many regions, such as Iraq, the necessary laboratory tests to confirm these diagnoses are often lacking, making clinical assessment even more important. The work highlights the challenges associated with diagnosing these conditions and emphasizes the need to utilize clinical skills and experience to achieve an accurate diagnosis. In light of new enzyme replacement therapies for certain mucopolysaccharidoses, the importance of precise clinical diagnosis is underscored to provide affected patients with access to potential treatments. This book is a valuable contribution to medical literature and offers insights into previously undocumented cases of these syndromes in Iraq.