The textbook "Metabolic Pathway Analysis towards Gene Therapy Advising" by Alaa Eldin Abdallah Yassin offers a comprehensive examination of the metabolic networks that play a central role in biology. It highlights the challenges associated with so-called "metabolic pathway holes," which are enzymatic reactions for which the corresponding genes are unknown. The work addresses the need for systematic data collection to fill these gaps and provides an innovative solution through the development of a central database, RGBMAPS. This database consolidates information from various sources, thereby facilitating analysis for researchers in this field. The book is aimed at professionals and students engaged in gene therapy and the analysis of biological networks.