The book "Microfluidic Very Large Scale Integration (VLSI)" provides a comprehensive overview of modern techniques for modeling, simulation, testing, compilation, and physical synthesis of microfluidic VLSI biochips. The authors, Paul Pop and Jan Madsen, present an innovative top-down methodology inspired by established VLSI methods in microelectronics. They develop a modeling framework for the components and architecture of biochips, as well as a high-level microfluidic protocol language. The book covers, among other topics, a topology-based model for biochip architecture and a sequencing graph model for biochemical applications. These techniques enhance programmability and automation, which are crucial for developers in the emerging market of large biochips.