The book "Multi-scale modeling and trans-level damage simulation method" offers a comprehensive examination of a newly developed adaptive multi-scale approach for simulating the failure of concrete-based structures. It addresses the development of random damage at the meso-scale up to structural failure using a three-hierarchical model. This model not only describes the various damage regions but also enables automated optimization, allowing for adjustments in the hierarchy during the computation process without user intervention. The strategies and theories presented provide insights into evolutionary damages and their effects on the structure, leading to a cost-effective and precise analysis. A case study demonstrates the application of the model by simulating the process from meso-scale damage to the structural failure of a specific construction. This methodology opens new perspectives for investigating the failure mechanisms of concrete structures.