The book "Nanofiber for Controlled Release of Antiviral Drug" offers a comprehensive analysis of nanofiber drug delivery systems aimed at enhancing the therapeutic efficacy of antiviral medications while reducing their toxicity. It explains how the design of multilayer nanofiber-based patches optimizes the localization of drugs in the body, thereby increasing the bioavailability of poorly bioavailable active substances. The authors, Amandeep Singh, Tara Singh Dogra, and Lovepreet Kaur Brar, present innovative approaches to encapsulating Acyclovir in polymeric nanopatches that allow for controlled and sustained release of the medication. These formulations exhibit pH-responsive release behavior in the small and large intestines and have demonstrated improved release and optimized pharmacokinetic profiles in pharmacokinetic studies conducted on rats. The book is aimed at professionals and students engaged in the development and application of nanofibers in drug delivery.