"New Methodologies in Organic Synthesis" is a specialized book that focuses on innovative approaches in organic synthesis. Written by Miguel Peña López, the work provides a comprehensive analysis of the synthesis of biologically active natural products, including Neomarinone, Fumaquinone, and Barrenazines A and B. The methods described in the book are based on the latest findings from the chemistry department at the Universidade da Coruña. Various synthetic strategies are presented that not only enable the effective extraction of these natural products but also confirm their structure during the isolation process. Additionally, a novel method for forming carbon-carbon bonds through palladium-catalyzed cross-coupling reactions of gold(I) organometallic compounds with different electrophiles is developed. This book is aimed at professionals and students interested in the latest developments in organic chemistry.