The book "Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Antiretroviral Drugs" offers a comprehensive and systematic analysis of the current literature on interactions of antiretroviral medications. It is aimed at both clinicians and researchers and includes easily accessible tables as well as chapter summaries that support decision-making in everyday clinical practice. The authors have developed an updated clinical decision algorithm specifically tailored to antiretroviral drugs. The identified interactions are interpreted in the context of known mechanisms derived from clinical, preclinical, and in vitro data. Furthermore, the clinical relevance of these interactions is systematically evaluated, and existing research gaps are discussed in light of potential future experiments. The book also provides extensive information on the epidemiology of HIV infections, diagnostics, and pharmacotherapy, as well as the fundamental pharmacology of individual antiretroviral agents.