The book "Pharmacophoric Utility of Oxygen Substituted Hydroxylamine Derivatives" by Prakash Prajapat offers a comprehensive examination of the synthesis of new organic molecules with enhanced therapeutic properties. It highlights the development of derivatives that exhibit optimal medicinal activity and describes the synthesis of novel molecules or drugs through the combination of various heterocyclic rings. The author places particular emphasis on economical, safe, and time-saving synthetic pathways that lead to the production of combinatorial molecules. In light of the challenges posed by deadly diseases such as malaria, tuberculosis, and cancer, the necessity to develop new, rapid, and environmentally friendly synthesis routes is underscored. The book provides valuable insights into reaction mechanisms and new chemical structures that are significant for drug discovery in medicinal chemistry. It is an essential work for professionals and students engaged in the development of innovative therapeutic approaches.