The book "Predictive Methods in Percutaneous Absorption" offers a comprehensive analysis of the quantitative models developed to describe the skin penetration process. It highlights advancements in the development and application of these models and provides critical evaluations as well as recommendations for their further development. Topics include an introduction to skin physiology, the underlying theories of skin absorption, and the physical, laboratory-based processes for generating data on skin absorption. This data is crucial for constructing mathematical models that describe the skin penetration process. Additionally, the book covers algorithms for skin permeability, including quantitative structure-activity relationships (QSARs or QSPRs), as well as the development of formula-based approaches to predict skin permeability. The book is aimed at researchers in academic and industrial pharmacy, as well as professionals in risk assessment and occupational safety, particularly in the fields of agrochemicals, bulk chemicals, and cosmetics.