The textbook "Prostate Cancer Treatment, Insilico approach" by Khaled Lotfy offers a comprehensive examination of computer-assisted molecular docking techniques used to analyze the interactions between drugs and biomacromolecules, particularly proteins. These techniques are crucial for understanding the biological functions of biomacromolecules and the therapeutic effects of medications. The book presents the application of molecular modeling, docking, and ADMET techniques to evaluate the potential of dimethylthiohydantoin derivatives as androgen antagonists. Additionally, it compares these compounds with hydroxyflutamide in the context of prostate cancer treatment. The results suggest that the compounds studied could serve as new approaches for the treatment of prostate cancer, as they possess androgen antagonist activity. These findings could be utilized in future experiments to investigate the interactions of these derivatives with the androgen receptor or in vivo studies to verify their therapeutic efficacy.