"Seminal Contributions to Information Systems Engineering" is a scholarly book that summarizes the most significant contributions to information systems engineering over a period of 25 years. On the occasion of the 25th International Conference on Advanced Information Systems Engineering (CAiSE) in 2013, the CAiSE steering committee presented a selection of groundbreaking works that were published at the conference. The authors, all esteemed researchers in their field, reflect on their work and its development over the years. The book provides a comprehensive analysis of the evolution of information systems engineering and highlights various aspects of modeling and designing information systems as well as requirements management. Additionally, a social network analysis of the research community is presented, offering interesting perspectives for future research directions.