The textbook "siRNA Delivery Methods" offers a comprehensive collection of advanced strategies for delivering siRNA that have been developed and refined over the years. Written by a team of internationally recognized authors, the book details a variety of successful methods for siRNA transfer, including peptide-based nanoparticles, liposomes, exosomes, polymers, aptamers, and viral vehicles. In the proven format of the "Methods in Molecular Biology" series, each tested protocol includes a brief introduction to the topic, a list of required materials and reagents, as well as step-by-step, easily reproducible laboratory protocols. Additionally, it provides troubleshooting tips and advice on avoiding common pitfalls. This comprehensive and authoritative work is aimed at researchers, educators, clinicians, and biotechnology professionals, offering a broad understanding of the challenges in siRNA delivery and their strategic solutions.