The book "Some 4-Thiazolidinones as Antimicrobial Agents" offers a comprehensive examination of the chemical compounds known as 4-Thiazolidinones. These compounds are derivatives of thiazolidine and are characterized by a carbonyl group at the 4-position. The structure and properties of these compounds can be significantly influenced by various substituents at the 2, 3, and 5 positions. The synthesis of these compounds typically occurs through a three-component reaction involving amines, carbonyl compounds, and mercaptoacetic acid. The book describes the reaction mechanisms that lead to the formation of 4-Thiazolidinones, including the formation of imines and the subsequent intramolecular cyclization. Furthermore, it addresses the diverse biological activities of these compounds, which range from antimicrobial to anti-inflammatory properties. This comprehensive analysis makes the book a valuable resource for professionals and students in the fields of chemistry and biosciences.