The book "The Subthalamic Nucleus" is a specialized text that delves deeply into the function and dysfunction of the subthalamic nucleus (STN) within the context of the basal ganglia. It provides a comprehensive analysis of the various neural pathways in which the STN plays a role, including the direct, indirect, and hyperdirect pathways. The book contains detailed information about the spontaneous activity of the STN as well as its responses to various stimuli, including high-frequency stimulation. The authors Tjitske Heida, Enrico Marani, and Kamen G. Usunoff explore the underlying ionic mechanisms and the effects of deep brain stimulation on the symptoms of Parkinson's disease. Furthermore, the connection between the pedunculopontine nucleus and the STN is highlighted, with neurotransmitter effects being replicated in cell cultures. The book offers both single and multi-compartment models of the STN and compares findings from different sections of the monograph to provide a comprehensive understanding of subthalamic functions.