The book "Vascular Ion Channels in Physiology and Disease" offers a comprehensive analysis of the role of ion channels in vascular tissues under normal and pathological conditions. Ion channels are crucial for the transport of ions across biological membranes and the generation of electrical signals in various tissues, including the brain, heart, and blood vessels. This publication highlights the critical functions of ion channels in regulating cell proliferation, insulin secretion, and intracellular signaling pathways in different cell types. Given that vascular anomalies are associated with serious conditions such as atherosclerosis, hypertension, and diabetes, a deeper understanding of the molecular mechanisms leading to vascular disorders is of great importance. This book represents the first comprehensive compilation of studies conducted over the past ten years to clarify the role of ion channels in various vascular diseases.