This 32GB RAM is 100% compatible with Supermicro A2SDi-2C-HLN4F. Information regarding memory configuration: The following technical specifications should be considered in advance: The device can accommodate non-ECC UDIMM (without Error-Correction-Code), ECC DIMM (with Error-Correction-Code), or RDIMM (Registered DIMM) RAM. RDIMM memory is recommended when large memory capacities are required. The different memory technologies (non-ECC UDIMM / ECC UDIMM / RDIMM) must not be mixed. If a memory upgrade is to be made with the existing RAM, it must be checked which memory technology (non-ECC UDIMM / ECC UDIMM / RDIMM) is currently in use. A higher memory clock of the memory module will automatically adjust to the memory clock set by the system. This can especially be the case with larger capacities.