The mouse generally works with Mac OS, however, the MX Anywhere 2S may experience connection problems via Bluetooth on newer Mac models with Apple Silicon (e.g. M1). A workaround is to use the Logitech Unifying Receiver, which is included in the scope of delivery, to connect the mouse via USB and connect it to the Logi Options software.

The MX Anywhere 2S supports Bluetooth and USB connection, is designed for right-handed users and has a manually adjustable DPI up to 4000. For an optimal Mac experience, however, we recommend the newer MX Anywhere 3S for Mac, which is specially optimised for macOS and offers a stable Bluetooth connection with macOS 11 or higher.