according to Canon EOS R50 (24.20 Mpx, APS-C / DX) SD / SDHC and SDXC cards can be used. The Extreme Pro is an SDXC card, so it is compatible with your R50.
However, why don't you want to use a larger card? e.g. 500 GB or even larger....

This card is fully compatible with the R50.

I use the card in a Canon EOS 90D and am very satisfied.