The book "Algorithms and Computation" presents the refereed proceedings of the 25th International Symposium on Algorithms and Computation (ISAAC 2014), which took place in December 2014 in Jeonju, Korea. It includes 60 revised full texts selected from 171 submitted papers, as well as two invited talks. The content of the volume focuses on a variety of topics relevant to computer science, including computational geometry, combinatorial optimization, graph algorithms, data structures and algorithms, and algorithmic complexity. The careful selection and review of the contributions ensure a high scientific quality and relevance for researchers and practitioners in the field of algorithms and computation.