The book "Biopacemaking" offers a comprehensive analysis of the development of bio-engineered pacemakers, which are of significant clinical and scientific interest. It examines how these innovative devices can overcome the limitations of conventional electronic pacemakers. A central theme of the book is the question of whether the complex structure of the sinoatrial node is essential for reliable pacemaker function or if simpler structures can also be effective. The authors present the current state of the art in the development of bio-engineered pacemakers and highlight genetic and cell-based engineering methods necessary for safe and stable implementation. Additionally, the challenges that must be addressed before bio-pacemaking can be utilized in clinical practice are discussed.