In the last thirty years, a new systemic concept of life has emerged at the forefront of science. The focus has shifted to complexity, networks, and organizational patterns, leading to a novel form of systemic thinking. This volume integrates the ideas, models, and theories underlying the systemic understanding of life into a unified, coherent framework. The authors take a broad look at history and various scientific disciplines, examining the emergence of central concepts such as autopoiesis, dissipative structures, social networks, and a systemic understanding of evolution. The implications of the systemic understanding of life for healthcare, management, and our global ecological and economic crises are also discussed. The text is primarily written for undergraduate students but is also essential reading for graduates and researchers interested in understanding the new systemic concept of life.