The challenge of managing increasing amounts of knowledge is often seen more as a threat than as an opportunity. Systemic knowledge management offers valuable and effective support in this regard, especially when it comes to achieving specific strategic goals. Helmut Willke combines theory and practice in this compact introduction to make them mutually beneficial. He first analyzes the components of systemic knowledge management: What does systemic mean? What does management entail? What does knowledge mean in this context? The following guiding questions focus on the themes of knowledge and learning, knowledge and ignorance, individual knowledge and organizational knowledge, all of which prove to be significant for practice. Finally, Willke describes the practical tools of systemic knowledge management and develops a clear guideline for implementation.