Depressions are characterized by feelings of sadness, loss of joy, lack of interest, emotional emptiness, lack of drive, and numerous physical complaints. For people suffering from chronic depression, these symptoms do not subside after a few weeks; rather, those affected have been enduring depressive symptoms for at least two years and have never been symptom-free for more than a few weeks at a time during this period. This guide is aimed at individuals who suffer from such chronic depression. It contains information for a better understanding of the condition, discusses the conditions that lead to chronic depression, and explains why it typically does not go away on its own. Additionally, it provides advice on what individuals can do to overcome chronic depression.