Few substances are perceived as psychoactive as coffee. This brown hot beverage made from the beans of the coffee plant is a psychostimulant par excellence and, moreover, a substance that can create interesting synergies when combined with numerous other psychoactives. The cultural history of coffee includes, alongside its pleasurable and intoxicating aspects, just as many twists and turns as the history of many other drugs. It all began when humans observed animals enjoying the coffee cherries. This marked the beginning of coffee's triumphal march and that of other caffeine-containing substances around the world. However, few know that coffee was once branded as a devilish poison and, in some areas, fell victim to early drug prohibition - this Smart Book discusses these topics as well.