The CRM Handbook Travel with Risk 2026 is a comprehensive guide specifically designed for travelers with health limitations and risks. It provides valuable information and practical tips that go beyond the general content of the CRM Handbook on Travel Medicine. The focus is on advising individuals with chronic illnesses, pregnant women, children, and seniors. The handbook covers more than 60 diseases and risk groups and offers detailed assessment and evaluation criteria for travel capability. Additionally, it addresses special precautionary measures, environmental influences, and activities to ensure a safe journey. The aftercare recommendations and information on medical infrastructure in over 60 countries are particularly helpful for travelers who rely on adequate medical care. Furthermore, important aspects such as bringing medications, import regulations for pharmaceuticals, and information on international health insurance are discussed. The handbook also includes up-to-date information on COVID-19 that is relevant for children, pregnant women, and seniors.