The topic of vaccination and its risks is becoming increasingly apparent to us. Many parents no longer want to expose their children to the high risk of side effects and permanent damage. On the other hand, they also do not want to leave their children unprotected. Homeopathy offers a proven alternative for gentle protection against childhood diseases. Specific remedies can stimulate the production of antibodies, as evidenced in the case of diphtheria. Valuable foundational knowledge is conveyed through the history of the discovery and research of homeopathic prophylaxis by Samuel Hahnemann and its studies over the past 200 years. Valued and applied in royal households: In Prussia, King Friedrich Wilhelm III ordered homeopathic prophylaxis against scarlet fever in 1838 - with great success. Unique is the rubella prophylaxis for pregnant women. For the first time, homeopathic prophylaxis and conventional vaccination are addressed together.