In Muriel's parents' house, Colin Sydney now lives with his family, one of the old neighbors of her and her mother Evelyn. Muriel primarily holds him and the social worker Isabel Field responsible for the events of ten years ago. The married Colin and Isabel were once a couple. Both emerged from their confrontations with Muriel and Evelyn not unscathed. At that time, Isabel not only gave up Colin but also her career, while Colin returned to his bleak marriage. By now, they have long resigned themselves to caring for elderly parents, rebellious teenagers, pregnant daughters, and unfaithful husbands. In contrast, Muriel's energy remains unbroken. Even though she calls herself crazy and stupid, she displays remarkable creativity in seeking revenge. She sneaks into the Sydneys' home with garish makeup.