The use and application of multimedia learning materials have increased significantly over the past 15 years. Statements regarding their effectiveness in terms of learning success hold particular importance. This work examines the effectiveness of multimedia learning materials. Through a comprehensive analysis of existing research and an original meta-analysis, statements about the effectiveness of multimedia learning materials are formulated. A primary focus is placed on differentiating both the forms of multimedia learning materials and the learning materials of the comparison groups (printed materials, teaching/lectures, no intervention). This allows for nuanced statements about the effectiveness of multimedia learning materials compared to traditional learning materials for the first time. It is shown that multimedia learning materials are more effective than traditional learning tools.