Theory and practice in the study of biology, chemistry, medicine, or pharmacy initially diverge significantly, especially regarding the integration into laboratory routines. This guide offers a practical and tested approach to mastering fundamental methods and techniques in the laboratory safely. A particular focus is placed on workplace safety. The contents include, among other topics: How to prepare precisely calibrated solutions? What does vessel adjustment mean? How to calculate the pH of a weak acid? What should be considered with high-pressure gases and pressure regulators? How do chromatography and electrophoresis work? Readers will receive a compact introduction to the soft skills of practical laboratory work, including material and equipment knowledge, as well as step-by-step instructions. This heavily revised new edition contains additional information.