This monograph deals with the organization of innovative agro-clusters in agriculture, the transition to digital systems, the implementation of profound structural changes, the challenges of cluster formation in agriculture, and their resolution. The monograph is aimed at the general public, students, practitioners, and researchers. It was discussed on April 27, 2021, during a meeting of the Department of Economics at the Namangan Institute of Engineering and Technology. It was approved and recommended for publication by Resolution No. 9 / 5.2, which was discussed at the board meeting of the Namangan Institute of Engineering and Technology on April 30, 2021.