The book "Enzymes in Nonaqueous Solvents" offers a comprehensive examination of enzymatic catalysis in non-aqueous solvents. It highlights the growing importance of enzymatic transformations in the synthesis of natural products, pharmaceuticals, fine chemicals, and food ingredients. The high selectivity and mild reaction conditions associated with enzymatic processes make this method an attractive alternative to conventional chemical syntheses, particularly in the production of complex bioactive compounds. The book addresses the challenges of the solubility of organic compounds in water and demonstrates how enzymes can operate effectively even under nearly anhydrous conditions. This insight has significantly expanded the application possibilities of enzymes in organic synthesis and offers new perspectives for utilizing cost-effective hydrolytic enzymes.