The book "Foundations of Health Information Engineering and Systems" offers a comprehensive collection of research findings that emerged from the Third International Symposium on the Foundations of Health Information Systems. The conference took place in 2013 in Macau, China, and brought together experts in the field to discuss current challenges and developments. This volume includes 19 revised full texts as well as an invited talk, selected from 22 submitted papers. The topics of the contributions cover a wide range, including interoperability, patient safety, device security, and formal methods in the context of HIV/AIDS and data protection. This careful selection and review of the works ensure that readers have access to relevant and up-to-date insights in the field of health informatics.