The identification of factors that can influence business success is a central goal of many empirical research projects in business administration. However, this also involves numerous methodological challenges. Martin Klarmann identifies 23 methodological problem areas in success factor research. These include, for example, common method bias, the specification of complex relationships, equivalent models, missing values, and omitted variables. Each problem area is first characterized, followed by a description of the problem diagnosis and potential solutions. The presentation culminates in clear recommendations for action. Additionally, empirical studies on open methodological questions are incorporated into the work for three of the problem areas.