This book provides a comprehensive insight into the current design of medium-sized business models, based on both theoretical and empirical foundations, as well as medium-sized specific approaches and forms of business model innovations that build upon them. These findings are particularly significant in light of increasing digitalization trends and a highly dynamic, changing competitive environment, not only for research but also for practice. Business model innovations are already being implemented by large corporations, which suggests that the pressure for change is also expected to rise for medium-sized enterprises. In this context, the book addresses the medium-sized sector as a somewhat under-researched subject in the context of business model innovation, drawing from the synthesis of theoretical insights.