The management of hospitals in the era of Diagnosis Related Groups requires a systematic and knowledge-based approach. Experience, intuition, and expertise in medicine, nursing, or general administration are no longer sufficient to lead the complex and dynamic operations of hospitals. This textbook develops tools for hospital management and integrates them into the context of hospital operations theory. Key areas of focus include management, controlling, logistics, information management, and strategy of hospital operations. The reader will not only learn quickly implementable methods but will also acquire a mindset: an evidence-based, goal-oriented, and sustainable management of hospital operations in a balance of efficiency and responsibility.