In Central Europe, over 210,000 people are diagnosed with white skin cancer (basal cell carcinoma, squamous cell carcinoma) each year, as well as over 20,000 people with black skin cancer. Fair-skinned individuals are particularly affected. Skin cancer encompasses all malignant changes in the skin, which can be categorized into different types. The most feared is black skin cancer, which is responsible for the majority of deaths. This guide presents all important types of skin cancer in words and images, discusses the course of the disease and treatment options, as well as prognoses. Early detection plays a crucial role, which is why this guide provides assistance for conducting personal examinations of suspicious skin areas. Additionally, risk factors are thoroughly examined to raise awareness of preventive measures.